Article

A clinical-anatomical signature of Parkinson’s Disease identified with partial least squares and magnetic resonance imaging

2017-07-27

Abstract excerpt

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by a wide array of motor and non-motor symptoms. It remains unclear whether neurodegeneration in discrete loci gives rise to discrete symptoms, or whether network-wide atrophy gives rise to the unique behavioural and clinical profile associated with PD. Here we apply a data-driven strategy to isolate large-scale, multivariate associations betwe...

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Literature Corpus work: 534b82aa-24a2-5b2e-8643-82ec04529619
DOI: 10.1101/168989

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