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Article

A reliable subtyping of de novo Parkinson disease: biomarkers, medication effects and longitudinal progression.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jul 2023

Sun Chaoliang, Xu Hengxi, Zhang Yuanchao, Zhang Yu

Abstract excerpt

Divergent clinical symptoms and pathological progression suggest multiple subtypes of Parkinson disease (PD). Here, we proposed a reliable PD subtyping approach that quantifies the disturbance of an individual patient to the reference structural covariance networks derived from healthy controls. We revealed two subtypes of de novo PD patients by using longitudinal data from the PPMI dataset. Compared to the...

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Identifiers

PMID: 38083250
DOI: 10.1109/EMBC40787.2023.10340372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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