Article

Extracellular adenosine enhances the ability of PMNs to kill <i>Streptococcus pneumoniae</i> by inhibiting IL-10 production

2019-07-26

Abstract excerpt

PMNs are crucial for initial control of Streptococcus pneumoniae (pneumococcus) lung infection; however, as the infection progresses their persistence in the lungs becomes detrimental. Here we explored why the anti-microbial efficacy of PMNs declines over the course of infection. We found that the progressive inability of PMNs to control infection correlated with phenotypic differences characterized by a decrease...

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Literature Corpus work: 533dfc5f-cf2d-5299-8407-d5f55205cc63
DOI: 10.1101/716456

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