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Article

<italic>Streptococcus pyogenes</italic> Infection and CD4+ T Cells Crosstalk Promote an Antigen-Presenting Cell-Like Phenotype in Neutrophils.

Journal of innate immunity - 1 Jan 2026

Riegner Anna, Siemens Nikolai

Abstract excerpt

INTRODUCTION: Neutrophils are the most abundant leukocytes in human blood and a key component of host defense against Streptococcus pyogenes (group A streptococci [GAS]). They are rapidly recruited to the site of infection, where they mediate phagocytosis, degranulation, and release of neutrophil extracellular traps, thereby influencing both bacterial clearance and tissue damage. Traditionally considered...

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Identifiers

PMID: 41875296
DOI: 10.1159/000551693
PMCID: PMC13200839

Genes

CD4
APC
CD40
CD86

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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