Article

Cellular and Transcriptional Signature of the Nasal Mucosa is Associated with Susceptibility to Pneumococcal Carriage in Older Adults

2023-11-21

Abstract excerpt

Streptococcus pneumoniae colonization in the upper respiratory tract is linked to pneumococcal disease development, predominantly affecting the very young and older adults. As the global population ages and comorbidities increase, there is a heightened concern about this infection. We investigated the immunological responses of older adults to pneumococcal controlled human infection by analysing the cellular compo...

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Literature Corpus work: 9ee26ede-d9cc-5f91-8646-b9f14615b945
DOI: 10.1101/2023.11.16.23298619

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