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Functional promiscuity of small multidrug resistance transporters from <i>Staphylococcus aureus</i> , <i>Pseudomonas aeruginosa</i> , and <i>Francisella tularensis</i>

2022-11-23

Abstract excerpt

<h4>ABSTRACT</h4> Small multidrug resistance (SMR) transporters efflux toxic substrates from bacterial cells and were recently divided into two subfamilies: specific toxic metabolite transporters and promiscuous drug exporters. These drug exporters are thought to function similarly to EmrE, the model system for this subfamily of SMR transporters. Studies of EmrE homologs indicate that they are able to confer resi...

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Literature Corpus work
52e9851c-7fee-58ad-a056-e79a00ee8e46
DOI
10.1101/2022.11.22.517605
Open publication

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