Article

Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in <i>Mycobacterium abscessus</i>

2024-08-24

Abstract excerpt

Mycobacterium abscessus is a pulmonary pathogen that exhibits intrinsic resistance to antibiotics, but the factors driving this resistance are incompletely understood. Insufficient intracellular drug accumulation could explain broad-spectrum resistance, but whether antibiotics fail to accumulate in M. abscessus and the mechanisms required for drug exclusion remain poorly understood. We measured antibiotic accumul...

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Literature Corpus work: c21af158-eb39-5560-9a90-6c4dc1ae1023
DOI: 10.1101/2024.08.23.609441

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