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Mechanism and Function of Type IV Secretion During Infection of the Human Host

6 May 2016

Abstract excerpt

Bacterial pathogens employ type IV secretion systems (T4SSs) for various purposes to aid in survival and proliferation in eukaryotic hosts. One large T4SS subfamily, the conjugation systems, confers a selective advantage to the invading pathogen in clinical settings through dissemination of antibiotic resistance genes and virulence traits. Besides their intrinsic importance as principle contributors to the...

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PMID: 27337453
DOI: 10.1128/microbiolspec.vmbf-0024-2015

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