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Evaluating the Link Between Efflux Pump Expression and Motility Phenotypes in <i>Pseudomonas aeruginosa</i> Treated with Virulence Inhibitors

2025-01-08

Abstract excerpt

Antibiotic resistance continues to rise as a global health threat. Novel anti-virulence strategies diminish the drive for evolutionary pressure, but still hinder a pathogen’s ability to infect a host. Treatment of the highly virulent Pseudomonas aeruginosa strain PA14 with virulence inhibitors (R-2 and R-6) elicited widely varying transcriptional profiles. Of interest, expression of a family of resistance-nodulat...

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Literature Corpus work
cef659a2-ddbd-5f96-afe8-1e9bfd4fb3fa
DOI
10.1101/2025.01.07.631739
Open publication

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Evaluating the Link Between Efflux Pump Expression and Motility Phenotypes in <i>Pseudomonas aeruginosa</i> Treated with Virulence InhibitorsDOI 10.1101/2025.01.07.631739
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