Article
Human gene expression variability and its dependence on methylation and aging.
BMC genomics - 7 Dec 2019
Bashkeel Nasser, Perkins Theodore J, Kærn Mads, Lee Jonathan M
Abstract excerpt
BACKGROUND: Phenotypic variability of human populations is partly the result of gene polymorphism and differential gene expression. As such, understanding the molecular basis for diversity requires identifying genes with both high and low population expression variance and identifying the mechanisms underlying their expression control. Key issues remain unanswered with respect to expression variability in human...
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