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Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 model of frontotemporal dementia

2024-03-10

Abstract excerpt

Metabolic disorders such as diabetes and obesity are linked to neurodegenerative diseases, with evidence of decreased brain glucose metabolism and insulin resistance in patients with dementia. Given the rising prevalence of age-related diseases, lifestyle adjustments and nutritional interventions are gaining interest. Dietary methionine restriction (MR) is a nutritional intervention that enhances insulin sensitivi...

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Literature Corpus work
52ba7b93-6c86-58c4-9f3d-9fcb7956e5b6
DOI
10.1101/2024.03.05.583295
Open publication

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Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 model of frontotemporal dementiaDOI 10.1101/2024.03.05.583295
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