Article

Metformin acts directly in the brain to slow features of neurodegeneration

2023-07-19

Abstract excerpt

<h4>ABSTRACT</h4> Dementia is a largely untreatable syndrome that is epidemiologically associated with metabolic diseases such as type 2 diabetes (T2D) and obesity. Drugs used to treat T2D such as metformin are inexpensive, safely given to millions of people, and have also been reported to slow neurodegeneration. We hypothesised that the neuroprotective benefits of metformin might extend to metabolically healthy...

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Literature Corpus work: 5932b993-b9e9-552d-aec3-8d7d57928058
DOI: 10.1101/2023.07.18.549549

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