Article

Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer’s disease mouse models

2024-09-10

Abstract excerpt

<h4>Summary</h4> Lifestyle factors modulate dementia risk. We investigated mechanisms of dementia risk reduction by emerging dietary ketogenic interventions. We show that distinct interventions, a medium-chain triglycerides (MCT)-enriched diet and a carbohydrate-free, high-fat diet (CFHF), improve cognition and dendritic spine density of memory-associated hippocampal neurons in two mouse models of Alzheimer’s dis...

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Literature Corpus work: a2c87caf-9997-5765-bd91-bfa67cdd1335
DOI: 10.1101/2024.09.04.610637

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