Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 mouse model of frontotemporal dementia.

Neurobiology of aging - 1 Feb 2025

Souza Matos Marina, Sil Annesha, Riedel Gernot, Platt Bettina, Delibegovic Mirela

Abstract excerpt

Metabolic disorders such as diabetes and obesity are linked to neurodegenerative diseases, with evidence of lower brain glucose metabolism and insulin resistance in dementia patients. Dietary methionine restriction (MR) is a nutritional intervention that enhances insulin sensitivity and delays ageing-associated metabolic alterations, however, its impact on neurodegenerative diseases is not fully understood. Here,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cognition
Share to Frontotemporal Dementia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycolysis

Share to Hippocampus

Share to Memory, Short-Term

Share to Methionine

Share to tau Proteins

Share to Tauopathies

Source

Identifiers

PMID: 39577250
DOI: 10.1016/j.neurobiolaging.2024.11.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 mouse model of frontotemporal dementia.PMID 39577250Read ↗

Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 model of frontotemporal dementiaSemantic proximity Read ↗

Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer’s disease mouse modelsSemantic proximity Read ↗

Dietary methionine restriction started late in life promotes healthy aging in a sex-specific mannerSemantic proximity Read ↗

Restriction of individual branched-chain amino acids has distinct effects on the development and progression of Alzheimer’s disease in 3xTg miceSemantic proximity Read ↗

1H NMR metabolomic signatures in five brain regions of the AβPPswe Tg2576 mouse model of Alzheimer's disease at four ages.Semantic proximity Read ↗

Molecular mechanisms of brain aging and neurodegenerative disorders: lessons from dietary restrictionSemantic proximity Read ↗

Molecular mechanisms of brain aging and neurodegenerative disorders: lessons from dietary restrictionSemantic proximity Read ↗

Characterizing Molecular and Synaptic Signatures in mouse models of Late-Onset Alzheimer’s Disease Independent of Amyloid and Tau PathologySemantic proximity Read ↗

Role of sex and high fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer’s diseaseSemantic proximity Read ↗

Dietary Fiber and Microbiota Metabolite Receptors Enhance Cognition and Alleviate Disease in the 5xFAD Mouse Model of Alzheimer’s DiseaseSemantic proximity Read ↗

Global metabolic reprogramming and sex-specific impact of caloric restriction in a mouse model of Alzheimer’s diseaseSemantic proximity Read ↗

Diet-induced metabolic and immune impairments are sex-specifically modulated by soluble TNF signaling in the 5xFAD mouse model of Alzheimer’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.