Article

A machine learning model for disease risk prediction by integrating genetic and non-genetic factors

2022-08-23

Abstract excerpt

Polygenic risk score (PRS) has been widely used to identify the high-risk individuals from the general population, which would be helpful for disease prevention and early treatment. Many methods have been developed to calculate PRS by weighted aggregating the phenotype-associated risk alleles from genome-wide association studies. However, only considering genetic effects may not be sufficient for risk prediction b...

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Literature Corpus work: 52a88ea4-5230-53d0-9926-4cbd0499e93c
DOI: 10.1101/2022.08.22.504882

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