Article

Astrocytes expressing M <sub>4</sub> muscarinic acetylcholine receptor regulate locomotion and survival in murine prion disease

2025-01-29

Abstract excerpt

Whilst there has been much focus on neuronally expressed muscarinic acetylcholine receptors (mAChRs), less attention has been paid to their expression and role in non-neuronal brain cells. Using genetically engineered mice, we identify a previously unappreciated subpopulation of astrocytes expressing the M4 mAChR subtype dispersed across various regions that include the brainstem, hypothalamus and, most abundantly...

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Literature Corpus work: 525deec6-8fee-5613-b1e2-ab01eb19621d
DOI: 10.1101/2025.01.29.635510

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Astrocytes expressing M <sub>4</sub> muscarinic acetylcholine receptor regulate locomotion and survival in murine prion diseaseDOI 10.1101/2025.01.29.635510Read

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