Article

Astrocytes regulate spatial memory in a sex-specific manner

2022-11-03

Abstract excerpt

Cognitive processes and neurocognitive disorders are regulated by astrocytes and have prominent sex differences. However, the contribution of astrocytes to sex differences is not known. We leveraged astrocyte-targeted gene editing and chemogenetics in adult mice to reveal that astrocytic glutamate receptors and other G protein-coupled receptors (GPCRs) modulate hippocampus-dependent cognitive function in a sexuall...

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Literature Corpus work: c8140f23-fef0-56c5-9688-0321df1d7118
DOI: 10.1101/2022.11.03.511881

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