Article

Properties of Glial Cell at the Neuromuscular Junction are Incompatible with synaptic repair in the SOD1 <sup>G37R</sup> ALS mouse model

2020-06-05

Abstract excerpt

<h4>ABSTRACT</h4> Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motoneurons in a motor-unit (MU) dependent manner. Glial dysfunction contributes to numerous aspects of the disease. At the neuromuscular junction (NMJ), early alterations in perisynaptic Schwann cell (PSC), glial cells at this synapse, may impact their ability to regulate NMJ stability and repair. Indeed, muscari...

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Literature Corpus work: a748cb4b-9f9d-503b-af41-014086aa4c16
DOI: 10.1101/2020.06.05.136226

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