Article

An in vitro model for studying CNS white matter: functional properties and experimental approaches

2019-01-29

Abstract excerpt

The normal development and maintenance of CNS white matter, and its responses to disease and injury, are defined by synergies between axons, oligodendrocytes, astrocytes and microglia, and further influenced by peripheral components such as the gut microbiome and the endocrine and immune systems. Consequently, mechanistic insights, therapeutic approaches and safety tests rely ultimately on in vivo models and clin...

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Literature Corpus work: 06b2a9bb-d243-5840-b78b-31be890c9d3b
DOI: 10.12688/f1000research.16802.1

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