Article
Novel muscarinic receptor mutant mouse models.
Handbook of experimental pharmacology - 1 Jan 2012
Wess Jürgen
Abstract excerpt
Muscarinic acetylcholine (ACh) receptors (mAChRs; M₁-M₅) regulate the activity of an extraordinarily large number of important physiological processes. During the past 10-15 years, studies with whole-body M₁-M₅ mAChR knockout mice have provided many new insights into the physiological and pathophysiological roles of the individual mAChR subtypes. This review will focus on the characterization of a novel...
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