Article

Molecular and functional properties of PFC astrocytes during neuroinflammation-induced anhedonia

2020-12-28

Abstract excerpt

Astrocytes are widely implicated in CNS diseases, but their contributions to disease related phenotypes remain incompletely explored. Anhedonia accompanies several neurological and psychiatric diseases, including major depressive disorder (MDD) and Alzheimer’s disease (AD), both of which are associated with neuroinflammation. In order to explore how neuroinflammation affects astrocytes, we assessed medial prefront...

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Literature Corpus work: 92e78d62-c39a-58a7-bedb-a151dc6f68b9
DOI: 10.1101/2020.12.27.424483

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