Article

Gene expression profiles complement the analysis of genomic modifiers of the clinical onset of Huntington disease

2019-07-11

Abstract excerpt

<h4>ABSTRACT</h4> Huntington disease (HD) is a neurodegenerative disorder that is caused by a CAG repeat expansion in the HTT gene. In an attempt to identify genomic modifiers that contribute towards the age of onset of HD, we performed a transcriptome wide association study assessing heritable differences in genetically determined expression in diverse tissues, employing genome wide data from over 4,000 patient...

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Literature Corpus work: 52367cca-27f8-5f9b-82c2-1a571d75e2da
DOI: 10.1101/699033

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