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Article

The Genetic Modifiers of Motor OnsetAge (GeM MOA) Website: Genome-wide Association Analysis for Genetic Modifiers of Huntington's Disease.

Journal of Huntington's disease - 1 Jan 2015

Correia Kevin, Harold Denise, Kim Kyung-Hee, Holmans Peter, Jones Lesley, Orth Michael, Myers Richard H, Kwak Seung, Wheeler Vanessa C, MacDonald Marcy E, Gusella James F, Lee Jong-Min

Abstract excerpt

BACKGROUND: Huntington's disease (HD) is a dominantly inherited disease caused by a CAG expansion mutation in HTT. The age at onset of clinical symptoms is determined primarily by the length of this CAG expansion but is also influenced by other genetic and/or environmental factors. OBJECTIVE: Recently, through genome-wide association studies (GWAS) aimed at discovering genetic modifiers, we identified loci...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26444025
DOI: 10.3233/JHD-150169
PMCID: PMC4753529

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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