Article

PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection

2024-06-22

Abstract excerpt

Parkinson’s disease (PD) is characterized by a protracted period of non-motor symptoms, including gastrointestinal (GI) dysfunction, which can precede the development of the cardinal motor deficits by decades. This long prodrome of disease is highly suggestive of immune cell involvement in the initiation of disease, but currently the field lacks robust model systems to study such mechanisms. It has been hypothesiz...

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Literature Corpus work: 517ce907-07b2-5ca4-98ea-c4ae8ecdba66
DOI: 10.1101/2024.06.18.598931

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PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infectionDOI 10.1101/2024.06.18.598931Read

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