Article
Gut-brain axis neurodegeneration in a Drosophila model of Parkinson’s disease is linked to mitochondrial dysfunction
2020-12-16
Abstract excerpt
<title>Abstract</title> <p>The innate immune response mounts a defence against foreign invaders, but the inappropriate induction of an innate immune response can cause diseases. Previous studies have provided ample evidence showing that mitochondria can be repurposed to promote inflammatory signalling. Damaged mitochondria can also trigger inflammation and promote diseases. Mutations in <italic>pink1</italic> cau...
Topics
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- Genetics, Aging, and Longevity in Model Organisms
- Insect and Pesticide Research
- Insect symbiosis and bacterial influences
- Invertebrate Immune Response Mechanisms
- Mitochondrial Function and Pathology
- Mosquito-borne diseases and control
- Neuroinflammation and Neurodegeneration Mechanisms
- Parkinson's Disease Mechanisms and Treatments
Identifiers and source
- Literature Corpus work
- 3fb21c9a-c70b-5dab-967e-e6fc51043c98
- DOI
- 10.21203/rs.3.rs-100637/v1
