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Identification of immune-mitophagy related gene in PD based on single-cell sequencing and Mendelian randomization

2025-05-07

Abstract excerpt

Parkinson’s disease (PD) involves dysregulated mitophagy and immuneresponses, though the underlying mechanisms remain unclear. To identify key genes linking these pathways, we integrated single-cell RNA sequencing (GSE157783) with Mendelian randomization(MR) analysis, screening mitophagy-related genes (MRGs) and immune-related genes (IRGs). Differential expression analysis across PD cell subpopulations, combined w...

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Literature Corpus work
d3c7b647-cadb-5d78-97e4-ae7c9cb06c07
DOI
10.1101/2025.05.01.651665
Open publication

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Identification of immune-mitophagy related gene in PD based on single-cell sequencing and Mendelian randomizationDOI 10.1101/2025.05.01.651665
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