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Article

Genome-wide DNA methylation in chronic myeloid leukaemia

2017-01-01

Abstract excerpt

Epigenetic alterations occur frequently in leukaemia and might account for differences in clinical phenotype and response to treatment. Despite the consistent presence of the BCR-ABL1 fusion gene in Philadelphia-positive chronic myeloid leukaemia (CML), the clinical course of patients treated with tyrosine kinase inhibitors (TKI) is heterogeneous. This might be due to differing DNA methylation profiles between pat...

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Literature Corpus work
515c5b72-ba1f-5e6b-a44c-2646c0693d9e
DOI
10.25560/67646
Open publication

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