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Article

DNA methylation profile in chronic myelomonocytic leukemia associates with distinct clinical, biological and genetic features.

Epigenetics - 1 Jan 2018

Palomo Laura, Malinverni Roberto, Cabezón Marta, Xicoy Blanca, Arnan Montserrat, Coll Rosa, Pomares Helena, García Olga, Fuster-Tormo Francisco, Grau Javier, Feliu Evarist, Solé Francesc, Buschbeck Marcus, Zamora Lurdes

Abstract excerpt

Chromosomal abnormalities are detected in 20-30% of patients with chronic myelomonocytic leukemia (CMML) and correlate with prognosis. On the mutation level, disruptive alterations are particularly frequent in chromatin regulatory genes. However, little is known about the consequential alterations in the epigenetic marking of the genome. Here, we report the analysis of genomic DNA methylation patterns of 64 CMML...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Leukemic

Share to Kaplan-Meier Estimate

Share to Leukemia, Myelomonocytic, Chronic

Share to Oligonucleotide Array Sequence Analysis

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Source

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Identifiers

PMID: 29160764
DOI: 10.1080/15592294.2017.1405199
PMCID: PMC5837079

Genes

TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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