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Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia

2 Feb 2017

Abstract excerpt

Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. AML is a heterogeneous malignancy characterized by distinct genetic and epigenetic abnormalities. Recent genome-wide DNA methylation studies have highlighted an important role of dysregulated methylation signature in AML from biological and clinical standpoint. In this review, we will outline the recent advances in the methylome...

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PMID: 28153026
DOI: 10.1186/s13045-017-0409-z

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