Article

Variation of Human Transfer RNA Demand and Supply

2026-02-27

Abstract excerpt

Codons function as translation units in open-reading-frames (ORF) of genes to encode for proteins. Transfer RNAs (tRNAs) mediate the connection of every codon to its cognate amino acid. Despite the cooperation between messenger and transfer RNA during translation, approaches to integrate codon usage and tRNA quantities remain to be established. Using matched mRNA- and tRNA-sequencing of peripheral blood cells, we...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 51408aad-05c4-55f2-8199-cbd457e0b0e3
DOI: 10.64898/2026.02.26.708130

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Variation of Human Transfer RNA Demand and SupplyDOI 10.64898/2026.02.26.708130Read

Position-dependent Codon Usage Bias in the Human TranscriptomeSemantic proximity Read

TissueCoCoPUTs: Novel Human Tissue-Specific Codon and Codon-Pair Usage Tables Based on Differential Tissue Gene Expression.Semantic proximity Read

Using protein-per-mRNA differences among human tissues in codon optimizationSemantic proximity Read

Mapping the Inter- and Intra-genic Codon Usage Landscape in <i>Homo sapiens</i>Semantic proximity Read

Human cellular homeostasis buffers <i>trans</i> -acting translational effects of heterologous gene expression with very different codon usage biasSemantic proximity Read

Third-nucleotide codon bias and synonymous codon bias define functional translational programs that shape human tissue and cancer proteomesSemantic proximity Read

Translational efficiency across healthy and tumor tissues is proliferation-relatedSemantic proximity Read

Codon usage and amino acid identity are major determinants of mRNA stability in humansSemantic proximity Read

Single-Cell Mapping of tRNA Expression Dynamics Across Human HematopoiesisSemantic proximity Read

Analysis at single-cell resolution identifies a stable mammalian tRNA-mRNA interface and increased translation efficiency in neuronsSemantic proximity Read

Transcriptomic, proteomic and functional consequences of codon usage bias in human cells during heterologous gene expressionSemantic proximity Read

Effect of mRNA/tRNA mutations on translation speed: Implications for human diseases.Semantic proximity Read