Article

Analysis at single-cell resolution identifies a stable mammalian tRNA-mRNA interface and increased translation efficiency in neurons

2021-06-28

Abstract excerpt

The correlation between codon and anticodon pools influences the efficiency of translation, but whether differences exist in these pools across individual cells is unknown. We determined that codon usage and amino acid demand are highly stable across different cell types using single-cell RNA-sequencing atlases of adult mouse and fetal human. After demonstrating the robustness of ATAC-sequencing for analysis of tR...

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Identifiers and source

Literature Corpus work: 30349176-2502-5ae3-8cba-60515d957b2a
DOI: 10.1101/2021.06.28.450167

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