Article

YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma

2018-02-23

Abstract excerpt

<h4> Abstract </h4> Transcriptomic profiling classifies pancreatic ductal adenocarcinoma (PDAC) into several molecular subtypes with distinctive histological and clinical characteristics. However, little is known about the molecular mechanisms that define each subtype and their correlation with clinical outcome. Mutant KRAS is the most prominent driver in PDAC, present in over 90% of tumors, but the dependence o...

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Literature Corpus work: 513b20bc-6d10-5c2d-a971-baf044c1b693
DOI: 10.1101/270314

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