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Article

Oncogenic signaling pathways in pancreatic ductal adenocarcinoma.

Advances in cancer research - 1 Jan 2023

Agrawal Rahul, Natarajan Kedar Nath

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is the most common (∼90% cases) pancreatic neoplasm and one of the most lethal cancer among all malignances. PDAC harbor aberrant oncogenic signaling that may result from the multiple genetic and epigenetic alterations such as the mutation in driver genes (KRAS, CDKN2A, p53), genomic amplification of regulatory genes (MYC, IGF2BP2, ROIK3), deregulation of...

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Identifiers

PMID: 37268398
DOI: 10.1016/bs.acr.2023.02.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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