Article

Pathway-specific genomic alterations in pancreatic cancer across diverse cohorts

2025-03-03

Abstract excerpt

<h4>Background/Objectives</h4> Pancreatic cancer (PC) is an aggressive malignancy with rising incidence and poor survival rates. While Hispanic/Latino (H/L) patients have a lower overall incidence compared to Non-Hispanic White (NHW) patients, they are diagnosed at younger ages, often present with more advanced disease, and experience worse survival outcomes. The molecular drivers underlying these disparities rem...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9fc85dc3-ca4b-5b1f-ad6e-14e33438d32c
DOI: 10.1101/2025.02.27.25323058

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pathway-specific genomic alterations in pancreatic cancer across diverse cohortsDOI 10.1101/2025.02.27.25323058Read

Pathway-Specific Genomic Alterations in Pancreatic Cancer Across Populations at Risk.Semantic proximity Read

Molecular alterations in TP53, WNT, PI3K, TGF-Beta and RTK/RAS pathways in gastric cancer among ethnically heterogeneous cohortsSemantic proximity Read

Molecular Alterations in TP53, WNT, PI3K, TGF-Beta, and RTK/RAS Pathways in Gastric Cancer Among Ethnically Heterogeneous CohortsSemantic proximity Read

Comparative genomic analysis of key oncogenic pathways in hepatocellular carcinoma among diverse populationsSemantic proximity Read

Comparative Genomic Analysis of Key Oncogenic Pathways in Hepatocellular Carcinoma Among Diverse PopulationsSemantic proximity Read

Molecular signature of pancreatic adenocarcinoma: an insight from genotype to phenotype and challenges for targeted therapy.Semantic proximity Read

An integrative mutational and network analysis of pancreatic cancer reveals key genes, and signalling pathways.Semantic proximity Read

Genetic landscape of pancreatic cancer: a narrative review.Semantic proximity Read

Pancreatic Cancer: Genetics, Screening, Prevention, and Treatment.Semantic proximity Read

Genomic determinants of biological aggressiveness and poor prognosis of pancreatic cancers: KRAS and beyond.Semantic proximity Read

Molecular and Genetic Basis of Pancreatic Carcinogenesis: Which Concepts May be Clinically Relevant?Semantic proximity Read

Alteration of Transforming Growth Factor β Signaling Pathway Predicts Worse Prognosis in Pancreatic Ductal Adenocarcinoma.Semantic proximity Read