Article
Relevance and actionable mutational spectrum in oral squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 May 2020
Jayaprakash Chinchu, Varghese Vinay Koshy, Jayaram Pradyumna, Chakrabarty Sanjiban, Kudva Adarsh, Ray Satadru, Satyamoorthy Kapaettu
Abstract excerpt
BACKGROUND: Screening for lesions in the oral cavity is critical for early diagnosis of oral squamous cell carcinoma (OSCC). Targeted next generation sequencing-based (NGS) mutation analysis of cancer driver genes becomes a reality for personalized medicine and cancer therapeutics. MATERIALS AND METHODS: In the present study, we have performed a targeted NGS-based mutation analysis of 50 known oncogenes and tumor...
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