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Somatic mutations in oral squamous cell carcinomas in 98 Japanese patients and their clinical implications.

Cancer treatment and research communications - 1 Jan 2021

Osawa Yuko, Aoyama Ken-Ichi, Hosomichi Kazuyoshi, Uchibori Masahiro, Tajima Atsushi, Kimura Minoru, Ota Yoshihide

Abstract excerpt

INTRODUCTION: The somatic mutational profile of oral squamous cell carcinoma (OSCC) among Japanese patients has been less investigated, partly because of the rarity of the tumor. Moreover, previous studies have either used formalin-fixed paraffin-embedded samples or lacked paired normal tissues. We aimed to determine somatic mutations in the exomes of 76 genes, including 50 driver genes of solid cancers and...

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Identifiers

PMID: 34563788
DOI: 10.1016/j.ctarc.2021.100456

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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