Article

Infiltrative classical monocyte-derived and <i>SPP1</i> lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritis

2024-03-13

Abstract excerpt

<h4>Background</h4> Kidney macrophage infiltration is a histological hallmark of vasculitic lesions and is strongly linked to disease activity in anti-neutrophil cytoplasmic antibodies (ANCA)-associated glomerulonephritis (AGN). The precise mechanisms by which kidney macrophages influence local inflammation and long-term damage remain largely unknown. <h4>Methods</h4> Here, we investigate kidney macrophage diver...

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Literature Corpus work: 51239515-500f-547d-819b-7cc34a47dd85
DOI: 10.1101/2024.03.13.584866

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Infiltrative classical monocyte-derived and <i>SPP1</i> lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritisDOI 10.1101/2024.03.13.584866Read

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