Article

The immune cell landscape in kidneys of lupus nephritis patients

2018-07-07

Abstract excerpt

<h4>ABSTRACT</h4> Lupus nephritis is a potentially fatal autoimmune disease, whose current treatment is ineffective and often toxic. To gain insights into disease mechanisms, we analyzed kidney samples from lupus nephritis patients and healthy controls using single-cell RNA-seq. Our analysis revealed 21 subsets of leukocytes active in disease, including multiple populations of myeloid, T, NK and B cells, demonstr...

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Literature Corpus work: 94a38d0b-dd46-599a-b08d-490419dcb7db
DOI: 10.1101/363051

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