Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deconvolution of synovial myeloid cell subsets across pathotypes and role of COL3A1+ macrophages in rheumatoid arthritis remission.

Frontiers in immunology - 1 Jan 2024

Hu Xuantao, Zhang Ziji, Long Lingli, Gu Minghu, Chen Weishen, Pan Baiqi, Wu Xiaoyu, Wang Chao, Li Chengxin, Zheng Linli, Sheng Puyi

Abstract excerpt

Background: Monocyte/macrophage (Mo/Mp) is a critical cell population involved in immune modulation of rheumatoid synovitis (RA) across different pathotypes. This study aims to investigate the contribution of Mo/Mp clusters to RA activity, and the biological function of particular subtypes in RA remission. Methods: We integrated single-cell RNA sequencing datasets from 4 published and 1 in-house studies using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Collagen Type III

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macrophages

Share to Phenotype

Share to Synovitis

Source

Open in PubMed Open full text

Identifiers

PMID: 38601143
DOI: 10.3389/fimmu.2024.1307748
PMCID: PMC11005452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deconvolution of synovial myeloid cell subsets across pathotypes and role of COL3A1+ macrophages in rheumatoid arthritis remission.PMID 38601143Read ↗

Analyzation of the Peripheral Blood Mononuclear Cells Atlas and Cell Communication of Rheumatoid Arthritis Patients Based on Single-Cell RNA-SeqSemantic proximity Read ↗

Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritisSemantic proximity Read ↗

Single-cell RNA-Seq analysis reveals cell subsets and gene signatures associated with rheumatoid arthritis disease activitySemantic proximity Read ↗

Defining Inflammatory Cell States in Rheumatoid Arthritis Joint Synovial Tissues by Integrating Single-cell Transcriptomics and Mass CytometrySemantic proximity Read ↗

Deciphering Cell-types and Gene Signatures Associated with Disease Activity in Rheumatoid Arthritis using Single Cell RNA-sequencingSemantic proximity Read ↗

Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.Semantic proximity Read ↗

Distinct tissue-niche localization and function of synovial tissue myeloid DC subsets in health, and in active and remission Rheumatoid ArthritisSemantic proximity Read ↗

A reference single-cell map of freshly dissociated human synovium in inflammatory arthritis with an optimized dissociation protocol for prospective synovial biopsy collectionSemantic proximity Read ↗

Associations between rheumatoid arthritis clinical factors with synovial cell types and statesSemantic proximity Read ↗

Integrative Spatial Proteomics and Single-Cell RNA Sequencing Unveil Molecular Complexity in Rheumatoid Arthritis for Novel Therapeutic TargetingSemantic proximity Read ↗

Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response PhenotypesSemantic proximity Read ↗

COVID-19 and Rheumatoid Arthritis share myeloid pathogenic and resolving pathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.