Article

Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis

2023-01-27

Abstract excerpt

<title>Abstract</title> <p>Patients with autoimmune vasculitis present with diverse organ-threatening symptoms, but the underlying immunological basis of the clinical heterogeneity remains poorly understood. We conducted single-cell transcriptome and surface proteome analyses using CITE-seq on 109,350 peripheral blood mononuclear cells (PBMCs) and CyTOF on 737,794 PBMCs from newly-onset patients with microscopic...

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Literature Corpus work: 2d4434df-2207-53dd-9024-0bf9559f5d0e
DOI: 10.21203/rs.3.rs-2466890/v1

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