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Intrarenal myeloid subsets associated with kidney injury are comparable in mice and patients with lupus nephritis

2023-06-25

Abstract excerpt

Resident macrophages and infiltrating monocytes in kidneys of patients with lupus nephritis are altered both in frequency and function relative to their counterparts in healthy kidneys. The extent to which mouse models might be useful in developing approaches to target these cells for treating lupus nephritis is poorly understood. Here, we studied four common lupus mouse models that share clinical, serologic, and...

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Identifiers and source

Literature Corpus work
4f398834-50c5-511e-92af-6f3c59f4dfc6
DOI
10.1101/2023.06.24.546409
Open publication

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Intrarenal myeloid subsets associated with kidney injury are comparable in mice and patients with lupus nephritisDOI 10.1101/2023.06.24.546409
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