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Deep profiling of lupus nephritis kidneys reveals dynamic changes in myeloid cells associated with disease progression

2025-12-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Lupus nephritis (LN) is a common, potentially fatal manifestation of systemic lupus erythematosus. We aim to gain new insights into the immune responses underlying LN and their relation to the histologic heterogeneity observed in this disease, focusing on myeloid cells. <h4>Methods</h4> Single-cell RNA-sequencing (scRNA-seq) was used to profile dissociated kidney samples fr...

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Literature Corpus work
e8e79560-9b06-5cb4-95a9-d07f4faac2f7
DOI
10.64898/2025.12.17.694954
Open publication

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Deep profiling of lupus nephritis kidneys reveals dynamic changes in myeloid cells associated with disease progressionDOI 10.64898/2025.12.17.694954
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