Article

Proliferating CLL cells express high levels of CXCR4 and CD5

2023-12-27

Abstract excerpt

Chronic Lymphocytic Leukaemia (CLL) is an incurable progressive malignancy of CD5+ B cells with a birth rate between 0.1-1% of the entire clone per day. However, the phenotype and functional characteristics of proliferating CLL cells remain incompletely understood. Here, we stained peripheral blood CLL cells for ki67 and DNA content and found that CLL cells in G1-phase have a CXCR4 lo CD5 hi phenotype, whilst CL...

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Literature Corpus work: 500464c6-9255-5067-9c00-f27ad5d684a8
DOI: 10.1101/2023.12.27.573410

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