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Article

High CXCR3 on Leukemic Cells Distinguishes IgHV mut from IgHV unmut in Chronic Lymphocytic Leukemia: Evidence from CD5high and CD5low Clones.

Journal of immunology research - 1 Jan 2020

Manukyan Gayane, Papajik Tomas, Mikulkova Zuzana, Urbanova Renata, Kraiczova Veronika Smotkova, Savara Jakub, Kudelka Milos, Turcsanyi Peter, Kriegova Eva

Abstract excerpt

Despite the shared pattern of surface antigens, neoplastic cells in chronic lymphocytic leukemia (CLL) are highly heterogeneous in CD5 expression, a marker linked to a proliferative pool of neoplastic cells. To further characterize CD5high and CD5low neoplastic cells, we assessed the chemokine receptors (CCR5, CCR7, CCR10, CXCR3, CXCR4, CXCR5) and adhesion molecules (CD54, CD62L, CD49d) on the CD5high and CD5low...

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Share to CD5 Antigens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Variable Region

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Receptors, Chemokine

Share to Receptors, CXCR3

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Source

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Identifiers

PMID: 32802894
DOI: 10.1155/2020/7084268
PMCID: PMC7322588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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