Article

Epigenome-based Splicing Prediction using a Recurrent Neural Network

2020-02-03

Abstract excerpt

Alternative RNA splicing provides an important means to expand metazoan transcriptome diversity. Contrary to what was accepted previously, splicing is now thought to predominantly take place during transcription. Motivated by emerging data showing the physical proximity of the spliceosome to Pol II, we surveyed the effect of epigenetic context on co-transcriptional splicing. In particular, we observed that splicin...

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Literature Corpus work: 4fb7bc61-d3f9-5f90-8690-4bfd2e1808da
DOI: 10.1101/2020.02.03.932251

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