Article

Pan-cell-type prediction of splicing patterns from sequence and splicing factor expression

2026-02-19

Abstract excerpt

<h4> A bstract </h4> Alternative splicing is a core determinant of cell-type-specific gene expression in humans, and its dysregulation contributes to many diseases including neurodegeneration, autoimmunity, and cancer. However, current deep learning models for predicting RNA expression from sequence are limited in how they handle cellular context dependence. These models typically achieve cell-type specificity...

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Literature Corpus work: 5ab395e1-04c2-5a0f-afe9-ac13c70ed5ab
DOI: 10.64898/2026.02.18.706660

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