Article

Predicting splicing patterns from the transcription factor binding sites in the promoter with deep learning

2023-04-09

Abstract excerpt

<h4>Background</h4> Alternative splicing is a crucial mechanism of post-transcriptional modification responsible for the transcriptome plasticity and proteome diversity of a metazoan cell. Although many splicing regulations around the exon/intron regions have been discovered, the relationship between promoter-bound transcription factors and the downstream alternative splicing remains largely unexplored. <h4>Resul...

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Literature Corpus work: 196ac166-8c2a-5487-864d-3f7bde9b998c
DOI: 10.1101/2023.04.09.536141

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