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Article

Improving splice site usage prediction with SPLAIRE

2026-06-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Alternative splicing, the mechanism by which intronic sequences are excised from pre-mRNAs to produce mature mRNA, affects >95% of human protein-coding genes and is a major driver of human disease states. The spliceosome, a protein-RNA complex responsible for splicing pre-mRNA, identifies candidate splice sites partly through the recognition of characteristic sequence motifs...

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Literature Corpus work
3b23f427-46d0-5706-93f3-096e81fe5acd
DOI
10.64898/2026.06.08.731019
Open publication

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