Article

Chromatin accessibility determines intron retention in a cell type-specific manner

2021-02-18

Abstract excerpt

<h4>Summary</h4> Dynamic intron retention (IR) in vertebrate cells is of widespread biological importance. Aberrant IR is associated with numerous human diseases including cancer. Despite consistent reports demonstrating intrinsic sequence features that predispose introns to become retained, conflicting findings about cell type-specific IR regulation demand a systematic analysis in a controlled experimental setti...

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Literature Corpus work: 6998ac90-3679-50fd-8233-837c647545ab
DOI: 10.1101/2021.02.17.431609

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