Article

Deep learning of the splicing (epi)genetic code reveals a novel candidate mechanism linking histone modifications to ESC fate decision

2017-09-15

Abstract excerpt

<h4>ABSTRACT</h4> Alternative splicing (AS) is a genetically and epigenetically regulated pre-mRNA processing to increase transcriptome and proteome diversity. Comprehensively decoding these regulatory mechanisms holds promise in getting deeper insights into a variety of biological contexts involving in AS, such as development and diseases. We assembled splicing (epi)genetic code, DeepCode, for human embryonic st...

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Literature Corpus work: 4a4232b8-4322-5b88-a7c6-1e689a781bb8
DOI: 10.1101/189183

Open publication

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